Invasive carcinoma of no special type

  • Razvan Fodoroiu Bucharest Emergency University Hospital, Bucharest, Romania
  • Mihai Cristian Dumitrașcu Bucharest Emergency University Hospital, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
  • Sandru Florica Elias Emergency University Hospital, Bucharest, Romania
Keywords: carcinoma, breast

Image Description

Invasive carcinoma of no special type, also known as invasive ductal carcinoma, represents almost 55% of invasive breast cancer. We present a case of a 72-year-old patient who was admitted in our department with a tumour-like left breast mass with erosion and retraction of the skin. The patient claimed she had the tumour for more than a year ago and that she felt no pain in the area. Clinical examination showed a single mass, with irregular margins and low mobility, with an erosive and necrotic aspect (Fig. 1). The patient presented ipsilateral axillary lymphadenopathy. Paraclinical investigations showed a CA 15-3 marker level of 13 U/ml (normal values: 0 - 31.3 U/ml). Ultrasound examination revealed a left breast mass (40-50 mm in diameter) with multiple microcalcifications and spiculated lesions that extended in the pectoral muscles, classified as BI-RADS 5 - highly suspicious of malignancy. Toraco-abdominal CT confirmed a 40 x 28 x 38 mm breast mass with necrosis and multiple enlarged lymph nodes with malignant aspect in the axillary, retropectoral and intrapectoral regions (Fig. 2; Fig 3). The biopsy result was invasive carcinoma of no special type, positive for estrogen and progesterone receptors, antigen Ki67, E-cadherin, and negative for epidermal growth factor receptor 2 (HER2). In this case, surgical treatment was not the first intention because of the local extension of the tumour and the malignant aspect of the lymph nodes. The patient was further referred to the oncology department for neoadjuvant chemotherapy in order to later receive surgical treatment.
How to Cite
Fodoroiu, R., Dumitrașcu, M., & Florica, S. (2019). Invasive carcinoma of no special type. Medical Image Database, 2(2), 19-20.